Creatine is largely accepted as an ergogenic aid in activities of short duration (less than 30 seconds) and of high intensity (2,3). In these studies activities such as 1RM bench press, 1RM leg press and anaerobic running capacity have seen significant increases. The human body utilizes three different energy systems when supplying energy for muscular contractions. They are the adenosine triphosphate-phosphocreatine (ATP-PC), glycolysis and the oxidative phosphorylation systems. The use of a creatine supplement has been proven to increase the creatine stores in the muscle fibers which allows for faster ATP production via the ATP-PC system (2,3). Research indicates a safe dosage consists of a 20g/day loading phase for 5-7 days with these daily doses being broken down into 5g ingested four times per day followed by a maintenance phase of 3-5g/day (1).
Health Risks
One concern with any nutritional supplement is the possibility of long-term and short-term health risks. Anecdotal evidence has linked creatine use to short-term health concerns such as Gastrointestinal (GI) Distress which can include vomiting and diarrhea and more serious long- term concerns such as muscle, liver and kidney damage. My review of the literature finds nothing to date that scientifically supports damage to the muscle, liver or kidneys (1,4,5). One study followed professional basketball players for three seasons, measuring various muscle, liver and kidney blood markers and found no significant outliers (5). Although the literature does not suggest GI distress to be of concern, one study did find that a dose of 10g/day consumed all at once caused slightly more GI distress in the form of diarrhea than those participants who took 10g/day but the 10g was broken into two doses of 5g taken 12 hours apart (4). But as mentioned in the introduction, 10g/day falls outside of the accepted healthy range of 5g/day (3,4).
Performance Enhancer or Diminisher?
As stated above, creatine supplementation aids the ATP-PC energy system and has been proven to benefit activities that are of high intensity and short duration, lasting 30 seconds or less (2,3). Activities such as football, short running and cycling sprints and weightlifting are just a few. Activities of longer durations that rely on the oxidative phosphorylation energy system have not been proven to benefit from a creatine supplement (3). There is conflicting evidence whether creatine causes an increase in bodyweight (2,3). This may be of concern if your activity is weight sensitive and one or two pounds of
bodyweight can have a detrimental effect on the outcome of your performance. There is also conflicting evidence about whether men and women benefit equally. One study showed that men’s anaerobic running capacity increased but the women participants’ did not (2).
Conclusion
The current research findings suggest the use of a creatine supplement to be safe and effective for healthy individuals participating in activities that require short burst of muscular strength and power.
References
1. Bemben, M.G., & Lamont, H. S. (2005). Creatine Supplementation and Exercise Performance: Recent Findings. Sports Medicine, 35(2), 107-125.
2. Fukuda, D.H., Smith, A. E., Kendall, K. L., Dwyer, T. R., Kerksick, C. M., Beck, T. W.,Cramer, J.T., Stout, J. R. (2010). The Effects Of Creatine Loading And Gender On Anaerobic Running Capacity. Journal Of Strength & Conditioning Research (Lippincott Williams & Wilkins), 24(7), 1826-1833.
3. Herda, T.J., Beck, T. W., Ryan, E. D., Smith, A. E., Walter, A. A., Hartman, M. J., Stout, J.R., Cramer, J. T. (2009). Effects Of Creatine Monohydrate And Polyethylene Glycosylated Creatine Supplementation On Muscular Strength, Endurance, And Power Output. Journal Of Strength & Conditioning Research (Lippincott Williams & Wilkins), 23(3), 818-826.
4. Ostojic, S. M., & Ahmetovic, Z. (2008). Gastrointestinal Distress After Creatine Supplementation in Athletes: Are Side Effects Dose Dependent? Research In Sports Medicine, 16(1), 15-22.
5. Schröder, H., Terrados, N., & Tramullas, A. (2005). Risk Assessment Of The Potential Side Effects Of Long-Term Creatine Supplementation In Team Sport Athletes. European Journal Of Nutrition, 44(4), 255-261.
Disclaimer: This posting does not include my recommendation to use creatine or my endorsement for any brand or manufacturer.







